PA 82 was designated on various state highways between Delaware and Baumstown at US 422 by 1930. The route it had in 1930 would be the route PA 82 would utilize for nearly 80 years. The only major change to the route prior to 2008 was the jurisdiction of the route through East Marlborough Township. On October 19, 1998, the Pennsylvania Department of Transportation (PennDOT) transferred maintenance of the route to the Township due to the Township wanting to make improvements to the roads without waiting through the PennDOT approval process.
Prior to 2008, PA 82 continued north through Elverson on Chestnut Street and entered Berks County. It was called Elverson Road, Twin Valley Road and Haycreek Road. In Birdsboro, PA 82 was called Furnace Street and had a small concurrency with Pennsylvania Route 724. PA 82 then terminated at a T-intersection with US 422 westbound.
On September 8, 1987, torrential rains flooded Hay Creek for days and destroyed several trestles that cross Hay Creek just south of Birdsboro. Over the coming months, local residents got used to the lack of traffic and fought to keep the road permanently closed, forcing PennDOT to forgo any possible bridge replacement. However, they did rebuild the bridge just south of Douglas Street. As a result, PA 82 was impossible to transverse from end to end. In late 2008, PennDOT decommissioned this section of PA 82 north of Elverson making the old section of PA 82 in Chester County SR 4082 and the section in Berks County SR 2082. The bulk of this area is now known as Berks County Park. Some GPS systems still mark this road as PA 82 and may not have the destroyed section of road blocked off on current maps. In September 2010, PennDOT decided to hand over the closed portion of the former PA 82 to local landowners.
When this section of PA 82 was decommissioned, PA 345 was extended north of its previous terminus in Birdsboro at PA 724 along PA 724 and then along the former routing of PA 82 to US 422.
Eklund, Bridget (October 21, 1998). "Revisiting Safety Along Rte. 82 In The Wake Of A Student's Death, East Marlborough Officials Want Added Measures To Keep Accidents From Happening". Philadelphia Inquirer. Retrieved January 10, 2014. "Since PennDot gave East Marlborough ownership on Monday of a 5.5-mile stretch of Route 82 from Mill Road to Route 926..."
"Township Closer To Makeover For Unionville's Main Street". Philadelphia Inquirer. October 16, 1998. Retrieved January 10, 2014. "'We can respond faster to the needs of the road and making it safer, say, by putting in a crosswalk,' Kaskey said, explaining why officials want to acquire that stretch of Route 82. 'It is much harder for the state to get around to doing these things.'"