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Ketipramine

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Ketipramine
Systematic (IUPAC) name
5-[3-(dimethylamino)propyl]-5,11-dihydro-10H-dibenzo[b,f]azepin-10-one
Clinical data
Legal status ?
Routes Oral
Identifiers
CAS number 17243-32-2
ATC code None
PubChem CID 28424
ChemSpider 26443
UNII U5C4H63K5U
Chemical data
Formula C19H22N2O 
Mol. mass 294.39 g/mol

Ketipramine (G-35,259), also known as ketimipramine or ketoimipramine, is a tricyclic antidepressant (TCA) that was tested in clinical trials for the treatment of depression in the 1960s but was never marketed. It differs from imipramine in terms of chemical structure only by the addition of a ketone group, to the azepine ring, and is approximately equivalent in effectiveness as an antidepressant in comparison.

See also

References

  1. Dictionary of organic compounds. London: Chapman & Hall. 1996. ISBN 0-412-54090-8. 
  2. Simeon J, Fuchs M, Nikolovski O, Bucci L (1970). "Ketipramine in the therapy of depression in outpatients". Psychosomatics 11 (4): 342–6. doi:10.1016/S0033-3182(70)71634-4. PMID 5459338. 
  3. Park S, Glick B, Floyd A, Gershon S (May 1971). "Ketipramine fumarate as compared to imipramine in depressed outpatients". Current Therapeutic Research, Clinical and Experimental 13 (5): 322–5. PMID 4998396. 
  4. Author Unknown (1971). Ann Reports Medicinal Chem V6 (v. 6). Boston: Academic Press. ISBN 0-12-040506-7. 


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